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جاري تحميل محتوى الصفحةpotaspirono 25 mg 20 tab
about spironolactone selective aldosterone antagonist antiandrogen potassium-sparing diuretic. mechanism of action of spironolactone spironolactone is a steroid with structural similarity to aldosterone which exerts it`s pharmacological actions by acting
Drug Monograph — spironolactone
echanism of Action Spironolactone and its active metabolites are specific pharmacologic antagonists of aldosterone, acting primarily through competitive binding of receptors at the aldosterone-dependent sodium-potassium exchange site in the distal convoluted renal tubule. Spironolactone causes increased amounts of sodium and water to be excreted, while potassium is retained. Spironolactone acts both as a diuretic and as an antihypertensive drug by this mechanism. It may be given alone or with other diuretic agents that act more proximally in the renal tubule.
هذه المعلومات الدوائية مُستخلصة من مصادر طبية موثوقة (FDA/Altibbi) وهي للتثقيف الصحي العام فقط، ولا تُغني عن استشارة الصيدلي أو الطبيب المختص. لا تبدأ أو توقف أو تغيّر جرعة أي دواء بدون إشراف طبي.