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جاري تحميل محتوى الصفحةsynobar face cleanser 150 ml
حموضة - قرحة معدة
Drug Monograph — rabeprazole sodium
echanism of Action Rabeprazole belongs to a class of antisecretory compounds (substituted benzimidazole proton-pump inhibitors) that do not exhibit anticholinergic or histamine H 2 -receptor antagonist properties, but suppress gastric acid secretion by inhibiting the gastric H + , K + ATPase at the secretory surface of the gastric parietal cell. Because this enzyme is regarded as the acid (proton) pump within the parietal cell, rabeprazole has been characterized as a gastric proton-pump inhibitor. Rabeprazole blocks the final step of gastric acid secretion. In gastric parietal cells, rabeprazole is protonated, accumulates, and is transformed to an active sulfenamide. When studied in vitro , rabeprazole is chemically activated at pH 1.2 with a half-life of 78 seconds. It inhibits acid transport in porcine gastric vesicles with a half-life of 90 seconds.
هذه المعلومات الدوائية مُستخلصة من مصادر طبية موثوقة (FDA/Altibbi) وهي للتثقيف الصحي العام فقط، ولا تُغني عن استشارة الصيدلي أو الطبيب المختص. لا تبدأ أو توقف أو تغيّر جرعة أي دواء بدون إشراف طبي.
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